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A woman suicide bomber killed at least 31 people and wounded 35 in a crowded market in the town of Musayab, 80 km (50 miles) south of Baghdad, on Friday, security sources said.
Islamic State claimed the attack, 30 km east of the Shi'ite holy city of Kerbala, as well as a suicide attack at a bus station in central Kerbala around the same time. It did not identify either bomber, in a statement on its Amaq news agency.
The hardline Sunni Muslim insurgents are on the brink of losing Mosul, their de-facto capital inIraq, to a US-backed Iraqi offensive launched in October.
The group is also on the backfoot in neighbouring Syria, retreating in the face of a US-backed, Kurdish-led military coalition attacking Raqqa, its capital there.
Iranian-backed paramilitaries are taking part in the campaign against Islamic State in Iraq, attacking the group in the border region near Syria.
Islamic State declared a self-styled "caliphate" over parts of Syria and Iraq three years ago.
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