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Consumption of walnuts may help suppress growth and survival of breast cancer, a study claims. The study, published in the journal Nutrition Research, found that consumption of two ounces of walnuts a day for about two weeks significantly changed gene expression in confirmed breast cancers.
According to W Elaine Hardman, from Marshall University in the US, Consumption of walnuts has slowed breast cancer growth and reduced the risk of mammary cancer in mice.
In this first clinical trial, women with breast lumps large enough for research and pathology biopsies were recruited and randomised to walnut consuming or control groups. Immediately following biopsy collection, women in the walnut group began to consume two ounces of walnuts per day until follow-up surgery.
Pathological studies confirmed that lumps were breast cancer in all women who remained in the trial. At surgery, about two weeks after biopsy, additional specimens were taken from the breast cancers.
The study showed activation of pathways that promote apoptosis or programmed cell death and cell adhesion and inhibition of pathways that promote cell proliferation and migration.
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